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FancyMancy

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  • 'World’s Smallest Atom-Memory Unit’ Created for Smaller, Faster, More Energy-Efficient Computing Chips
  • Scientific Breakthrough! New Device Makes Memristors Act as Neurons
  • Space travel impairs mitochondrial function
  • Comprehensive Multi-omics Analysis Reveals Mitochondrial Stress as a Central Biological Hub for Spaceflight Impact
  • Study finds hyperbaric oxygen treatments reverse aging process
  • Hyperbaric oxygen treatments halt aging of blood cells and reverse aging process
  • Scientists Identify Gene Responsible for Human Ageing
  • Researchers identify gene responsible for cellular aging
  • Scientists create diamonds at room temperature in minutes
  • Scientists defy nature to make insta-bling at room temperature
  • Earth’s Water Came from Enstatite Chondrite-Like Asteroids, Study Suggests
  • Meteorite study suggests Earth may have been wet since it formed
  • The Earth may have been wet from the very start



'World’s Smallest Atom-Memory Unit’ Created for Smaller, Faster, More Energy-Efficient Computing Chips
30/11/2020
Smaller processors enable manufacturers to make more compact computers and phones.

Researchers have created the smallest memory device yet, an advance that may lead to faster, smaller, and more energy-efficient electronic chips for consumer electronics and brain-inspired computing.

The scientists from the University of Texas at Austin in the US also found the physics that unlocks dense memory storage capabilities for these tiny devices.

In the research (https://archive.is/iPWYT), published recently in the journal Nature Nanotechnology, the scientists reduced the size of what was then the thinnest memory storage device, shrinking the cross section area down to just a single square nanometre.

According to the researchers, getting a handle on the physics that pack dense memory storage capability into these devices enabled them to make the device much smaller.

They said ultrasmall holes in the material provide the key to unlocking the high-density memory storage capability.

"When a single additional metal atom goes into that nanoscale hole and fills it, it confers some of its conductivity into the material, and this leads to a change or memory effect," explained Deji Akinwande, a co-author of the study.

Though they used the compound molybdenum disulfide, also known as MoS2, as the primary nanomaterial in their study, the researchers believe the discovery could apply to hundreds of related atomically thin materials.

Smaller processors enable manufacturers to make more compact computers and phones, they said, adding that shrinking down chips also decreases their energy demands and increases capacity.

This means faster and smarter devices that take less power to operate, the scientists explained.

The original device, dubbed "atomristor" by the researchers, was at the time the thinnest memory storage device ever recorded, with a single atomic layer of thickness.

However, shrinking the memory device is not just about making it thinner but also building it with a smaller cross-sectional area, they added.

"The scientific holy grail for scaling is going down to a level where a single atom controls the memory function, and this is what we accomplished in the new study," Akinwande said.

The new device falls under the category of memristors, an area of memory research, centred around electrical components with the ability to modify resistance between its two terminals without a need for a third terminal in the middle.

According to the researchers, these can be smaller than currently used memory devices and boast more storage capacity.

They said the new memristor promises a capacity of about 25 terabits per square centimetre, which is about 100 times higher memory density per layer compared with commercially available flash memory devices.
https://archive.is/rVa0M



Scientific Breakthrough! New Device Makes Memristors Act as Neurons
02/10/2020

A memristor is a device that regulates the flow of electrical current in a circuit and remembers the amount of charge that flowed through it. They are non-volatile devices, which means they can retain memory without power. Recently, experts have made a breakthrough in memristors that can make it act like a neuron.

Engineers have been trying to copy the power efficiency and quirky computational skills of the brain for many years, but they cannot do it. They do not have a device that can act like a neuron, one whose behavior is more complicated than any device has ever made.

A new device invented by Hewlett Packard Laboratories' Suhas Kumar, Texas A&M's R. Stanley Williams, and Ziwen Wang, a Stanford student, has met all those requirements. The device outputs simple spikes, burst os spike, self-sustained oscillations, and other processes usually found in the brain using a simple DC voltage as an input.

Most devices can only perform simple spikes, so this new invention is extraordinary. The researchers published their study in the journal Nature (https://archive.is/466y9).

Memristor Breakthrough
The novel device combines resistance capacitance and Mott memristor, with the nanometers-thin niobium oxide (NbO2) layer as the most vital part. A memristor is a device that can hold memories of the charge that previously flowed through them, in the form of resistance.

Engineers have only explored in nanoscale devices the properties of the materials in a Mott transition that could go between insulating and conducting based on their temperature.

Inside the memristor, the transition happens in a nanoscale silver of NbO2 in which when DC voltage is applied, it heats up slightly. It causes it to transition from insulating to conducting. The charge then builts up in the capacitance pours through once that transition happens.

Slowly the device cools, which triggers a transition back to insulating. The result resembles a neuron's action potential in which a spike current flows in the device.

Williams said that they have been working for five years to get that result and noted that many things are going on in that one nanoscale material.

Leon Chua, the inventor of memristor, predicted that there would be regions of chaotic behavior discovered between areas where behavior is unstable if the possible device parameters are mapped. Devices can exist that can act as a neuron at the edge of some of these chaotic regions.

Read Also: Curly the Robot Competes With Professional Curling Athletes (https://archive.is/Fa25r)

Applying it to today's machines
According to Williams, it was Kumar who fine-tuned the material and physical parameters of the device to find a combination that works. This invention is the type that cannot be found accidentally because everything has to be perfect before seeing this characteristic. But once it is made, it becomes very robust and reproducible.

The researchers tested the device by building spiking versions of Boolean logic gates, and then they made a small analog optimization circuit.

According to the researchers, there is still a lot more to do to turn these into practical devices and make them bigger to challenge today's machines. Williams and Kumar plan to explore other possible materials that experience Mott transitions at different temperatures, considering that shifts in NbO2 happen only at 800 degrees Celsius, which only occurs in nanometers thin layer. Scaling it up to millions of devices could pose a big problem.

Meanwhile, other scientists are also researching using vanadium oxide, which can transition at 60 degrees Celsius, better than NbO2. However, that temperature might be too low given that systems in the data center operate ta 100 degrees Celsius, Williams said. There could also be other materials that can be used to achieve the same result, which could be very interesting.
https://archive.is/RGZdL



Space travel impairs mitochondrial function
30/11/2020

Spaceflight is hard on the human body, and our mitochondria are not immune to its pressures.

Space travel presents unique challenges to biology, primarily extended exposure to microgravity and high levels of cosmic radiation. Mitochondria are the organelles responsible for the cell's energy demands, converting sugar into energy, facilitating life. How they react to these challenges is poorly understood. New research from a multidisciplinary team including researchers from the National Aeronautics and Space Administration (NASA), California, and the Georgetown Lombardi Comprehensive Cancer Centre, Washington DC, led by Dr Afshin Beheshti, unites the impact of two threats on this organelle.

'What we found over and over was that something is happening with the mitochondria regulation that throws everything out of whack' Dr Beheshti explained (https://archive.is/MS7zb).

Dr Beheshti's team analysed a breadth of 'multi-omics' data, made possible by NASA's GeneLab, an online 'omics' database consisting of transcriptome, proteome and epigenome data from a variety of experiments involving spaceflight. The group employed this database to take a systems biology approach, looking at multiple species, including humans and mice, isolated human cells, and a variety of tissues, such as muscle and liver.

Their curated dataset was then queried for trends which correlated and overlapped between these diverse samples. The common thread which emerged from the data on gene expression, protein content and epigenetic status of the genome was the signature of changes to mitochondrial activity, across nearly all the samples.

Dr Beheshti 'was completely surprised to see that mitochondria are so important, because they weren't on our radar'. Despite this, the impact of spaceflight on mitochondria was not completely unknown, having previously been observed in soybean seedlings (https://archive.is/ewtAD).

Analysis of blood and urine samples from 59 astronauts and from the NASA Twin Study (https://archive.is/Ne11S) provided physiological evidence of altered mitochondrial function to support the omics data.

Their work, published in the journal Cell (https://archive.is/AZ3uO), shows a universally negative impact of spaceflight on mitochondria and the team believe that impacts on mitochondria, given their critical role in energy generation, could underpin other effects of spaceflight on biology, such as disruption to circadian rhythms and cardiovascular health. Previously identified problems with liver function in astronauts, for example, can now be linked to impaired mitochondria. The team propose a combination of exercise, drugs and diet as a means of minimising the impact of spaceflight on mitochondria in future.

The precise mechanism underlying this impact on mitochondria remains to be uncovered. Nonetheless, the groundwork laid by this study will facilitate future space exploration, which inevitably dictates prolonged periods of spaceflight for humans.
https://archive.is/UW6vC



Comprehensive Multi-omics Analysis Reveals Mitochondrial Stress as a Central Biological Hub for Spaceflight Impact
25/11/2020

Highlights
  • Multi-omics analysis and techniques with NASA’s GeneLab platform
  • The largest cohort of astronaut data to date utilized for analysis
  • Mitochondrial dysregulation driving spaceflight health risks
  • NASA Twin Study data validates mitochondrial dysfunction during space missions

Summary
Spaceflight is known to impose changes on human physiology with unknown molecular etiologies. To reveal these causes, we used a multi-omics, systems biology analytical approach using biomedical profiles from fifty-nine astronauts and data from NASA’s GeneLab derived from hundreds of samples flown in space to determine transcriptomic, proteomic, metabolomic, and epigenetic responses to spaceflight. Overall pathway analyses on the multi-omics datasets showed significant enrichment for mitochondrial processes, as well as innate immunity, chronic inflammation, cell cycle, circadian rhythm, and olfactory functions. Importantly, NASA’s Twin Study provided a platform to confirm several of our principal findings. Evidence of altered mitochondrial function and DNA damage was also found in the urine and blood metabolic data compiled from the astronaut cohort and NASA Twin Study data, indicating mitochondrial stress as a consistent phenotype of spaceflight.

Graphical Abstract
se1kNZ5.png


...
https://archive.is/hTEKS



Study finds hyperbaric oxygen treatments reverse aging process
25/11/2020

6jEVUVa.gif

Human chromosomes (grey) capped by telomeres (white). Credit: PD-NASA; PD-USGOV-NASA

A new study from Tel Aviv University (TAU) and the Shamir Medical Center in Israel indicates that hyperbaric oxygen treatments (HBOT) in healthy aging adults can stop the aging of blood cells and reverse the aging process. In the biological sense, the adults' blood cells actually grow younger as the treatments progress.

The researchers found that a unique protocol of treatments with high-pressure oxygen in a pressure chamber can reverse two major processes associated with aging and its illnesses: the shortening of telomeres (protective regions located at both ends of every chromosome) and the accumulation of old and malfunctioning cells in the body. Focusing on immune cells containing DNA obtained from the participants' blood, the study discovered a lengthening of up to 38% of the telomeres, as well as a decrease of up to 37% in the presence of senescent cells.

The study was led by Professor Shai Efrati of the Sackler School of Medicine and the Sagol School of Neuroscience at TAU and Founder and Director of the Sagol Center of Hyperbaric Medicine at the Shamir Medical Center; and Dr. Amir Hadanny, chief medical research officer of the Sagol Center for Hyperbaric Medicine and Research at the Shamir Medical Center. The clinical trial was conducted as part of a comprehensive Israeli research program that targets aging as a reversible condition.

The paper was published in Aging on November 18, 2020.

"For many years, our team has been engaged in hyperbaric research and therapy—treatments based on protocols of exposure to high-pressure oxygen at various concentrations inside a pressure chamber," Professor Efrati explains. "Our achievements over the years included the improvement of brain functions damaged by age, stroke or brain injury.

"In the current study, we wished to examine the impact of HBOT on healthy and independent aging adults, and to discover whether such treatments can slow down, stop or even reverse the normal aging process at the cellular level."

The researchers exposed 35 healthy individuals aged 64 or over to a series of 60 hyperbaric sessions over a period of 90 days. Each participant provided blood samples before, during and at the end of the treatments, as well as some time after the series of treatments concluded. The researchers then analyzed various immune cells in the blood and compared the results.

The findings indicated that the treatments actually reversed the aging process in two of its major aspects: The telomeres at the ends of the chromosomes grew longer instead of shorter at a rate of 20% to 38% depending on the cell type; and the percentage of senescent cells in the overall cell population was reduced significantly—by 11%-37% depending on cell type.

"Today, telomere shortening is considered the 'holy grail' of the biology of aging," Professor Efrati says. "Researchers around the world are trying to develop pharmacological and environmental interventions that enable telomere elongation. Our HBOT protocol was able to achieve this, proving that the aging process can in fact be reversed at the basic cellular-molecular level."

"Until now, interventions such as lifestyle modifications and intense exercise were shown to have some inhibiting effect on telomere shortening," Dr. Hadanny adds. "But in our study, only three months of HBOT were able to elongate telomeres at rates far beyond any currently available interventions or lifestyle modifications. With this pioneering study, we have opened a door for further research on the cellular impact of HBOT and its potential for reversing the aging process."

Explore further
New hyperbaric oxygen therapy protocol can improve cognitive function of older adults (https://archive.is/Zgel1)

bui6iCa.png

https://archive.is/AmPS0



Hyperbaric oxygen treatments halt aging of blood cells and reverse aging process
22/11/2020

First clinical trial reverses two biological processes associated with aging in human cells.

YrknmYN.png

Image credit: AFTAU

...

The research paper is available at the journal’s web site here (https://archive.is/WwWV8).
https://archive.is/4B1c7

I was wondering if it would mention telomeres... and just when you thought Michael Jackson was right, the jew goes and says something. Let's not forget what's at the forefront of the jew's mind - "How can we make many shekels from this? We make a lot of shekels from funerals and cremations; this would give us a lot more shekels!"



Scientists Identify Gene Responsible for Human Ageing
04/12/2020

New research (https://archive.is/nO8hA) from the University of Wisconsin-Madison, published in Stem Cells, has identified a gene which regulates the ageing of human mesenchymal stem/stromal cells (MSCs).

Reversing Ageing
Cellular reprogramming can reverse ageing in Mesenchymal stem/stromal cells (MSCs). However, the molecular mechanisms by which this is achieved are not well understood. This recent study supported previous findings, demonstrating that rejuvenation was possible by cellular reprogramming. Furthermore, their findings enhanced the understanding of MSC ageing and associated disease. These results provide insight into potential pharmacological strategies to reduce or reverse the ageing process (https://archive.is/wUmjt).

Key Findings
The researchers extracted MSCs from human synovial fluid and reprogrammed them into induced pluripotent stem cells (iPSCs). They then transformed these iPSCs back into MSCs, in effect rejuvenating the MSCs. When comparing the rejuvenated MSCs to the original, non-rejuvenated cells, they found the cellular hallmarks of ageing were greatly reduced in reprogrammed cells. This reduction in ageing-related activities suggests a reversal of cell ageing has occurred.

Next, the scientists genetically analysed cells to investigate any changes in global gene expression as a result of the rejuvenation. They found that the expression of the GATA6 protein was repressed in reprogrammed cells.

The repression of GATA6 also led to an increase in the activity of the sonic hedgehog (SHH) protein and the FOXP1 protein, both essential for early development. Thus, the GATA6/SHH/FOXP1 pathway appears to be a key mechanism which regulates MSC ageing and rejuvenation.

Finally, the team confirmed that OCT4 and KLF4 (two of the four reprogramming genes used to derive iPSCs) were able to regulate GATA6 activity. This is consistent with several previous studies.

Future Direction
Overall, the study demonstrated that MSCs undergo substantial molecular and genetic changes as a result of cellular reprogramming. These changes indicate the amelioration of cell ageing. Most significantly, the outlining of the GATA6/SHH/FOXP1 pathway as a mechanism for cellular age-related activities could have broad implications in regenerative medicine.
https://archive.is/6mQG3



Researchers identify gene responsible for cellular aging
30/11/2020
I9fhZtA.jpg

When mesenchymal stem/stromal cells (MSCs) age, the transcription factor GATA6 is increasingly produced in the cell to induce aging response. By transcription factor-based cellular reprogramming, aged MSCs are rejuvenated with a reduction in GATA6 effects on cellular aging. Credit - AlphaMed Press

Cellular reprogramming can reverse the aging that leads to a decline in the activities and functions of mesenchymal stem/stromal cells (MSCs). This is something that scientists have known for a while. But what they had not figured out is which molecular mechanisms are responsible for this reversal. A study released today in STEM CELLS appears to have solved this mystery. It not only enhances the knowledge of MSC aging and associated diseases, but also provides insight into developing pharmacological strategies to reduce or reverse the aging process.

The research team, made up of scientists at the University of Wisconsin-Madison, relied on cellular reprogramming—a commonly used approach to reverse cell aging—to establish a genetically identical young and old cell model for this study. "While agreeing with previous findings in MSC rejuvenation by cellular reprogramming, our study goes further to provide insight into how reprogrammed MSCs are regulated molecularly to ameliorate the cellular hallmarks of aging," explained lead investigator, Wan-Ju Li, Ph.D., a faculty member in the Department of Orthopedics and Rehabilitation and the Department of Biomedical Engineering.

The researchers began by deriving MSCs from human synovial fluid (SF-MSCs)—that is, the fluid found in the knee, elbow and other joints—and reprogramming them into induced pluripotent stem cells (iPSCs). Then they reverted these iPSCs back to MSCs, in effect rejuvenating the MSCs. "When we compared the reprogrammed MSCs to the non-rejuvenated parental MSCs, we found that aging-related activities were greatly reduced in reprogrammed MSCs compared to those in their parental lines. This indicates a reversal of cell aging," Dr. Li said.

The team next conducted an analysis of the cells to determine if there were any changes in global gene expression resulting from the reprogramming. They found that the expression of GATA6, a protein that plays an important role in gut, lung and heart development, was repressed in the reprogrammed cells compared to the control cells. This repression led to an increase in the activity of a protein essential to embryonic development called sonic hedgehog (SHH) as well as the expression level of yet another protein, FOXP1, necessary for proper development of the brain, heart and lung. "Thus, we identified the GATA6/SHH/FOXP1 pathway as a key mechanism that regulates MSC aging and rejuvenation," Dr. Li said.

"Identification of the GATA6/SHH/FOXP1 pathway in controlling the aging of MSCs is a very important accomplishment," said Dr. Jan Nolta, Editor-in-Chief of STEM CELLS. "Premature aging can thwart the ability to expand these promising cells while maintaining function for clinical use, and enhanced knowledge about the pathways that control differentiation and senescence is highly valuable."

To determine which of the Yamanaka transcription factors (four reprogramming genes used to derive iPSCs) were involved in repressing GATA6 in the iPSCs, the team analyzed GATA6 expression in response to the knockdown of each factor. This yielded the information that only OCT4 and KLF4 are able to regulate GATA6 activity, a finding consistent with that of several previous studies.

"Overall, we were able to demonstrate that SF-MSCs undergo substantial changes in properties and functions as a result of cellular reprogramming. These changes in iPSC-MSCs collectively indicate amelioration of cell aging. Most significantly, we were able to identify the GATA6/SHH/FOXP1 signaling pathway as an underlying mechanism that controls cell aging-related activities," Dr. Li said.

"We believe our findings will help improve the understanding of MSC aging and its significance in regenerative medicine," he concluded.

Explore further
Human iPSC-derived MSCs from aged individuals acquire a rejuvenation signature (https://archive.is/Mn2c9)
https://archive.is/oxiKP



Scientists create diamonds at room temperature in minutes
20/11/2020
EeOhePE.jpg

PHD scholar Xingshuo Huang from the Australian National University holds the diamond anvil that the team used to make the lab diamonds.

Diamonds might be forever, but that doesn't mean they have to take eons to form.
The gemstones are usually created after carbon is crushed and heated far beneath the Earth's surface over billions of years -- which is what makes them so coveted.
Now, scientists in Australia say they have sped up the process into just a matter of minutes -- and at room temperature.

An international team of researchers led by the Australian National University (ANU) and RMIT University in Melbourne, Australia said Wednesday they have created two types of diamond at room temperature by using high pressure equivalent to 640 African elephants balancing on the tip of a ballet shoe.

The researchers said they were able to create two types of structurally distinct diamonds -- one similar to those typically worn in jewelery, and another type called Lonsdaleite, which is found naturally at the site of meteorite impacts and is harder than most diamonds.
Synthetic diamonds are not themselves new, and have already been created in labs since the 1940s in a bid to find cheaper, ethical and environmentally friendly stones.

But researchers were excited to create such diamonds at room temperature, especially the harder Lonsdaleite diamond, which has the potential to be used to cut through "ultra-solid" materials on mining sites, they said.

"Creating more of this rare but super useful diamond is the long-term aim of this work," said Xingshuo Huang, an ANU scholar working on the project. "Being able to make two types of diamonds at room temperature was exciting to achieve for the first time in our lab."
Lab grown diamonds are usually created by carbon being subjected to intense heat (https://archive.is/b9Qp8).

A huge twisting, sliding force
To form the diamonds, researchers applied immense pressure to create a "twisting or sliding force" that they believe caused the carbon atoms to move into place, said Jodie Bradby, a physics professor at ANU.

"Natural diamonds are usually formed over billions of years, about 150 kilometers (about 93 miles) deep in the Earth where there are high pressures and temperatures above 1,000 degrees Celsius (1,832 degrees Fahrenheit)," she said. "The twist in the story is how we apply the pressure."

Y5PIciz.jpg

This close up image shows the diamond "rivers".

Dougal McCulloch, physics professor at RMIT who co-lead the research, and his team then used advanced electron microscopy techniques to take slices from the experimental samples to better understand how they were formed.

When the team studied the samples they found veins of both regular and the Lonsdaleite diamonds running through.

"Seeing these little 'rivers' of Lonsdaleite and regular diamond for the first time was just amazing and really helps us understand how they might form," McCulloch said.
Researchers from The University of Sydney and Oak Ridge National Laboratory, in Tennessee, US were also involved in the research.

Related Article
phssq7z.jpg

This entrepreneur says he's making diamonds 'from the sky'
https://archive.is/w04D0



Scientists defy nature to make insta-bling at room temperature
An international team has made diamonds in minutes in a laboratory at room temperature – a process that normally takes billions of years, huge amounts of pressure and super-hot temperatures.

2U1ISSA.png

PhD candidate Brenton Cook and Professor Dougal McCulloch in the RMIT Microscopy and Microanalysis Facility

...
https://archive.is/ovxhJ

It has been known that commercially-purchasable diamonds can be created in laboratories/factories, as well. I saw something which showed the size of a diamond in a pressing machine thing, and the machine around the tiny-in-comparison diamond, was big, sort of like having a giant's hand crushing a usual-sized almont "nut" (cough) or something. Oh, and did I say that they still cost a lot of shekels to buy, despite them being mass-produced now?!

According to the Mohs scale, diamond is the strongest substance. It can be cut only by another diamond (the last I knew).

Along the lines of the "twisting or sliding force" which they believe moves atoms into place - I wondered if we could get some mercury, freeze it to low-enough temperatures, and remove one of its protons thereby turning it from mercury into gold, a sort of futuristic Midas touch or philosopher's stone (because these things are "legend" and "primitive", of course). It is, apparently, "possible to transmute mercury into gold by making it unstable so it decays [https://archive.is/wx6iV]. Decay, freeze, whatever.




Earth’s Water Came from Enstatite Chondrite-Like Asteroids, Study Suggests
LOFXRME.jpg

A piece of the enstatite chondrite meteorite Sahara 97096. Image credit - Christine Fieni/Laurette Piani/French National Museum of Natural History.

A type of meteorite called an enstatite chondrite has similar isotopic composition to terrestrial rocks and thus may be representative of the material that formed Earth. A new study (https://archive.is/Mb1tk) published in the journal Science shows that these meteorites contain sufficient hydrogen to have delivered to Earth at least three times the mass of water in its oceans.

Enstatite chondrites are space rocks forged from the nebula that formed the Solar System.

They are rare, making up only about 2% of known meteorites in collections. But their isotopic similarity to terrestrial rocks make them particularly compelling.

They have similar oxygen, titanium and calcium isotopes as Earth, and the new study showed that their hydrogen and nitrogen isotopes are similar to Earth’s, too.

“Our discovery shows that the Earth’s building blocks might have significantly contributed to the Earth’s water,” said Dr. Laurette Piani, a researcher at the Université de Lorraine.

“Hydrogen-bearing material was present in the inner Solar System at the time of the rocky planet formation, even though the temperatures were too high for water to condense.”

The building blocks of Earth are often presumed to be dry. They come from inner zones of the Solar System where temperatures would have been too high for water to condense and come together with other solids during planet formation.

The meteorites provide a clue that water didn’t have to come from far away.

“The most interesting part of the discovery for me is that enstatite chondrites, which were believed to be almost dry, contain an unexpectedly high abundance of water,” said Dr. Lionel Vacher, a postdoctoral researcher at Washington University in St. Louis.

“If enstatite chondrites were effectively the building blocks of our planet — as strongly suggested by their similar isotopic compositions — this result implies that these types of chondrites supplied enough water to Earth to explain the origin of Earth’s water, which is amazing!”

The team also proposes that a large amount of the atmospheric nitrogen — the most abundant component of the Earth’s atmosphere — could have come from the enstatite chondrites.

“Only a few pristine enstatite chondrites exist: ones that were not altered on their asteroid nor on Earth,” Dr. Piani said.

“In our study, we have carefully selected the enstatite chondrite meteorites and applied a special analytical procedure to avoid being biased by the input of terrestrial water.”

Coupling conventional mass spectrometry and secondary ion mass spectrometry allowed the scientists to precisely measure the content and composition of the small amounts of water in the meteorites.

“Prior to this study, it was commonly assumed that enstatite chondrites formed close to the Sun,” Dr. Piani said.

“These chondrites were thus commonly considered dry, and this frequently reasserted assumption has probably prevented any exhaustive analyses to be done for hydrogen.”

Laurette Piani et al. 2020. Earth’s water may have been inherited from material similar to enstatite chondrite meteorites. Science 369 (6507): 1110-1113; doi: 10.1126/science.aba1948
https://archive.is/3CxAL



Meteorite study suggests Earth may have been wet since it formed
Enstatite chondrite meteorites, once considered 'dry,' contain enough water to fill the oceans -- and then some
https://archive.is/6rNyu



The Earth may have been wet from the very start
A new study finds the rocks that first formed Earth carried with them enough hydrogen for three times the water we have today.
https://archive.is/KGn7y



Mistakes and errors in the articles above are by the respective authours of the articles.
 
We are entering a wonderful age of discovery and for science, and this is a reason to oppose the enemy now to avoid the worst later.

Just imagine the possibilities of all of this. The enemy has to fail at all costs to drag down the United States. A lot of great things will arise in the next decades.

The only thoughts of the slimy jew among all of these wonderful things, is to just make people drones or something. They never care for the bigger picture.
 
I forgot to add -

Ageing is Reversible - at Least in Human Cells and Live Mice
https://ancient-forums.com/viewtopic.php?f=3&t=26409


HP. Hoodedcobra666 said:
We are entering a wonderful age of discovery and for science, and this is a reason to oppose the enemy now to avoid the worst later.

Just imagine the possibilities of all of this. The enemy has to fail at all costs to drag down the United States. A lot of great things will arise in the next decades.

The only thoughts of the slimy jew among all of these wonderful things, is to just make people drones or something. They never care for the bigger picture.
Seriously - what a time to be alive. Cor blimey - well, not literally! More like Cors elucida'emey (Gods, elucidate (for) me)! When will we have christians crying "Witch! Witch!"?! :roll: :lol: jewsus was supposed to have walked on watcr; ergo, jewsus is a witch! jewsus performed magic, and the magi were also supposed to have been magicians... Stupid christians... Maybe we will find another tribe (the Amondawa tribe was found relatively recently, who were supposed to have had no concept of time) who are ignorant and consider us evil for having knowledge. Oh, wait - that's (((the tribe)))!
 
But scientific advancement is evil, how dare these discoveries be made to the betterment of humankind and further expose the falseness of the Lard Thy Gawd in the self-destructive humility of the holololy people. I miss the middle ages when we'd shit into a bucket and dine with diseased rats and piss into our drinking water.
 
FancyMancy said:
  • Comprehensive Multi-omics Analysis Reveals Mitochondrial Stress as a Central Biological Hub for Spaceflight Impact
Space travel impairs mitochondrial function

Spaceflight is hard on the human body, and our mitochondria are not immune to its pressures.

Space travel presents unique challenges to biology, primarily extended exposure to microgravity and high levels of cosmic radiation. Mitochondria are the organelles responsible for the cell's energy demands, converting sugar into energy, facilitating life. How they react to these challenges is poorly understood. New research from a multidisciplinary team including researchers from the National Aeronautics and Space Administration (NASA), California, and the Georgetown Lombardi Comprehensive Cancer Centre, Washington DC, led by Dr Afshin Beheshti, unites the impact of two threats on this organelle.

'What we found over and over was that something is happening with the mitochondria regulation that throws everything out of whack' Dr Beheshti explained (https://archive.is/MS7zb).

Dr Beheshti's team analysed a breadth of 'multi-omics' data, made possible by NASA's GeneLab, an online 'omics' database consisting of transcriptome, proteome and epigenome data from a variety of experiments involving spaceflight. The group employed this database to take a systems biology approach, looking at multiple species, including humans and mice, isolated human cells, and a variety of tissues, such as muscle and liver.

Their curated dataset was then queried for trends which correlated and overlapped between these diverse samples. The common thread which emerged from the data on gene expression, protein content and epigenetic status of the genome was the signature of changes to mitochondrial activity, across nearly all the samples.

Dr Beheshti 'was completely surprised to see that mitochondria are so important, because they weren't on our radar'. Despite this, the impact of spaceflight on mitochondria was not completely unknown, having previously been observed in soybean seedlings (https://archive.is/ewtAD).

Analysis of blood and urine samples from 59 astronauts and from the NASA Twin Study (https://archive.is/Ne11S) provided physiological evidence of altered mitochondrial function to support the omics data.

Their work, published in the journal Cell (https://archive.is/AZ3uO), shows a universally negative impact of spaceflight on mitochondria and the team believe that impacts on mitochondria, given their critical role in energy generation, could underpin other effects of spaceflight on biology, such as disruption to circadian rhythms and cardiovascular health. Previously identified problems with liver function in astronauts, for example, can now be linked to impaired mitochondria. The team propose a combination of exercise, drugs and diet as a means of minimising the impact of spaceflight on mitochondria in future.

The precise mechanism underlying this impact on mitochondria remains to be uncovered. Nonetheless, the groundwork laid by this study will facilitate future space exploration, which inevitably dictates prolonged periods of spaceflight for humans.
https://archive.is/UW6vC

I wonder if former HP.mageson's sermon on Taurus Field(He stated Torus meant Taurus) or Earth field is a reason why this is happening.

Basically to put it simply free-energy engines like mercury engines found on Vimanas produce not just free energy plus a null field, anti-gravity. They also seem to generate a Taurus Field or Earth Field to protect inhabitants of the vessel with protection from the background of Space.

I wonder if these guys were told about said device or maybe the free-energy gennys produce the field already. I'm not entirely sure if the engine produces the field or the engine requires a special device to be attached to generate the necessary field. It's possible that with the Gods they invented some way of generating a normal Taurus/Earth Field with the genny/engine and pipe it through the main field of anti-gravity i.e. the entire vessel inside and out.

Non-the less I agree with HP.Cobra it's interesting that all these things are popping in. I wouldn't be surprised if we even provided some kabalistic support. I'm glad these people are alive to tell their tale albeit probably is gonna be buried under the internet (((schlep))) to make sure people don't know about this. Hopefully with Covid lockdowns people are educating themselves on said subject and bringing it up all the shit the enemy tosses in to make sure said research remains buried.
 
HP. Hoodedcobra666 said:
We are entering a wonderful age of discovery and for science, and this is a reason to oppose the enemy now to avoid the worst later.

Just imagine the possibilities of all of this. The enemy has to fail at all costs to drag down the United States. A lot of great things will arise in the next decades.

The only thoughts of the slimy jew among all of these wonderful things, is to just make people drones or something. They never care for the bigger picture.

I gotta say this. I'm worried. Not only in the case that jews would be allowed to play with us in further ways through these technologies, but also very much in the case ANYONE else would be. Humans (most of them I guess) as they are now are just too unevolved spiritually and would probably see these inventions and technology as another way to apply newly acquired power over other Humans. We have too many people that still don't even care about Animal lives, consuming much more than they need to, and wasting meat they never hunted in the first place. Imagine what they'll do to other Humans if they knew they could get away with it because of a fancy invention.
I don't mean to be the one that bitches about all new technology, and I for one admit that I have no clue how our Gods and technology itself intersect.
I know HP Maxine stated that science has been purposely halted and stopped as it will one day 'converge' and be probably indistinguishable by magick, but at least for now I guess I just can't see how that would happen. Chips, enhancing technologies that work on the Human body and all that... I can GLADLY do without.
I had the luxury of never being vaccinated, and keep FAR away from anything that doesn't belong in my body, meaning "anything I wasn't BORN with", and I'll keep it this way.

Again, I don't have a clue how our Fathers and Mothers live, if they use technology at all and in what measure. When I think of the Gods I think of absolute perfection of the Soul, a perfect, immortal Body that fears nothing, and a Mind that knows not to rely on anything other than itself. As a child I was fond of fancy digital gizmos, but growing up I learned to value natural things infinitely more, growing suspicious of everything that was "pulled" on me... like today's 5G monstrosities and microchips just to mention the most inhuman examples.

Reversing the aging process? We have the Magnum Opus.

Diamonds in minutes? Who fucking needs them? I know I don't.

And so on... hey, maybe I'm short sighted and can't see the wonders that these things will bring us... but I don't buy it. We don't need 'enhancements' or anything like that in order to live long and happy lives.. why would we even meditate if there were fancy devices that allow us to do anything?

So, no thank you. I'll pass.

HAIL SATAN FOREVER!
 
Satan_is_our_Father666 said:
HP. Hoodedcobra666 said:
We are entering a wonderful age of discovery and for science, and this is a reason to oppose the enemy now to avoid the worst later.

Just imagine the possibilities of all of this. The enemy has to fail at all costs to drag down the United States. A lot of great things will arise in the next decades.

The only thoughts of the slimy jew among all of these wonderful things, is to just make people drones or something. They never care for the bigger picture.
...

HAIL SATAN FOREVER!

Your worry is more based on what could wrong rather than what could go right. I tend to think of things in a more positive light. And science will assist on many things, but can breed monstrosities. The same thing goes for spiritual power. Some people may use it for nefarious purposes, but it can't be that it's restrained as there is no good either.

Problems arise when all of the scientific advancement is not followed up with spiritual awareness. But this line will meet the other in the future after time passes. As we are going right now, there is hope for this at least.

The combination of technological and scientific discovery is a manifestation of one aspect and level of the mind. If it follows up with the rest of the spiritual advancement, there shouldn't be fear.

IMO, the enemy being in power and trying to bind these things, is the only worrisome thing.

You can be in the Stone Age and people will still do braindead things that can cause mass destruction. What changes with technology is the magnitude of this. The only way to avoid this is to change humans and in the case of the enemy, remove them from power.
 
HP. Hoodedcobra666 said:
Problems arise when all of the scientific advancement is not followed up with spiritual awareness.

HP. Hoodedcobra666 said:
The only way to avoid this is to change humans and in the case of the enemy, remove them from power.

Fully agree on that then. I guess I'm only seeing clearly what has already happened "thanks to technology", weaponry, 5G, microchips, abusing genetics to clone Animals and force them into short lives of slavery and suffering, not to mention vivisection as "research".... stuff like that just gets to me as much as to cast away all my I-don't-wanna-destroy issues and choose to master an Element JUST to bring death to those responsible for these inhuman and barbaric actions.

I guess you're right about spirituality being used with nefarious intentions too.. the fake "god" is proof enough for this, so ...yeah.. the Races need to awake and become sensitized to what actually matters. I can't wait until this Planet is RID of jews. I can't remember how it was when the Gods were here and we lived in the previous Golden Age... I guess this is one of the times where my blindness makes me unable to understand things. I would welcome technology IF it were only used for good and making our lives easier and better, able to give us enough to live happily and all the time in the world to meditate and practice magick... I just fear I'm talking about a future not too close as people today, still xtians, still pisslamic and generally weak minded and sheeple alike, DON'T have what it takes to take a weapon and not point it to the next 'goyim' who has more goodies and money then them.

Kinda feels like the Stone Age, you know... sometimes I wonder about how Satan must feel to see his creation behaving in such idiotic manner.. I know the Gods know the future but if they didn't I wouldn't be surprised had they given up on us ("us" meaning the greatest majority, the non-Satanists).

Another worry (quickly said) is that the benefits of technology, even if used for good, would make many lazy and relying SOLELY on technology, forgetting to meditate, forgetting to explore their Souls. We already see that all the time with people that prefer to play videogames than understand what Spiritual Satanism is, preferring to shoot a fireball in a damn game than learning pyrokinesis in real life.

Maybe I'm just expecting too much too soon, and I'll make a rather severe teacher when I eventually evolve into what we're supposed to become. I just can't tolerate weakness of character, laziness and ignorance. I guess this is why I fear CURRENT Humans getting sci-fi technology. It would be just like giving a little child his father's gun. Hope I'm not overexaggerating worrying like this. I had bad visions and dreams regarding "super technology" before, and I would hate it to discover that technology will be used against us in some way. It certainly is the main enemy trend these days.

HAIL SATAN FOREVER!
 
Ghost in the Machine said:
But scientific advancement is evil, how dare these discoveries be made to the betterment of humankind and further expose the falseness of the Lard Thy Gawd in the self-destructive humility of the holololy people. I miss the middle ages when we'd shit into a bucket and dine with diseased rats and piss into our drinking water.
Depends if it is used for good things or used for evil things. You think those aliens controlling this are not going to use this technology to do evil things?
 
Science is beautiful when it is well applied for good and not to enslave. I hope that when the empire of David Strait falls completely we can use science and technology to raise our energies in the same way that we can use technology for war with the RTR, that is, it was unthinkable to do a spiritual ritual using paint in a computer, there are no limits between science and spirituality.
 
FancyMancy said:
  • 'World’s Smallest Atom-Memory Unit’ Created for Smaller, Faster, More Energy-Efficient Computing Chips
  • Scientific Breakthrough! New Device Makes Memristors Act as Neurons
  • Space travel impairs mitochondrial function
  • Comprehensive Multi-omics Analysis Reveals Mitochondrial Stress as a Central Biological Hub for Spaceflight Impact
  • Study finds hyperbaric oxygen treatments reverse aging process
  • Hyperbaric oxygen treatments halt aging of blood cells and reverse aging process
  • Scientists Identify Gene Responsible for Human Ageing
  • Researchers identify gene responsible for cellular aging
  • Scientists create diamonds at room temperature in minutes
  • Scientists defy nature to make insta-bling at room temperature
  • Earth’s Water Came from Enstatite Chondrite-Like Asteroids, Study Suggests
  • Meteorite study suggests Earth may have been wet since it formed
  • The Earth may have been wet from the very start



'World’s Smallest Atom-Memory Unit’ Created for Smaller, Faster, More Energy-Efficient Computing Chips
30/11/2020
Smaller processors enable manufacturers to make more compact computers and phones.

Researchers have created the smallest memory device yet, an advance that may lead to faster, smaller, and more energy-efficient electronic chips for consumer electronics and brain-inspired computing.

The scientists from the University of Texas at Austin in the US also found the physics that unlocks dense memory storage capabilities for these tiny devices.

In the research (https://archive.is/iPWYT), published recently in the journal Nature Nanotechnology, the scientists reduced the size of what was then the thinnest memory storage device, shrinking the cross section area down to just a single square nanometre.

According to the researchers, getting a handle on the physics that pack dense memory storage capability into these devices enabled them to make the device much smaller.

They said ultrasmall holes in the material provide the key to unlocking the high-density memory storage capability.

"When a single additional metal atom goes into that nanoscale hole and fills it, it confers some of its conductivity into the material, and this leads to a change or memory effect," explained Deji Akinwande, a co-author of the study.

Though they used the compound molybdenum disulfide, also known as MoS2, as the primary nanomaterial in their study, the researchers believe the discovery could apply to hundreds of related atomically thin materials.

Smaller processors enable manufacturers to make more compact computers and phones, they said, adding that shrinking down chips also decreases their energy demands and increases capacity.

This means faster and smarter devices that take less power to operate, the scientists explained.

The original device, dubbed "atomristor" by the researchers, was at the time the thinnest memory storage device ever recorded, with a single atomic layer of thickness.

However, shrinking the memory device is not just about making it thinner but also building it with a smaller cross-sectional area, they added.

"The scientific holy grail for scaling is going down to a level where a single atom controls the memory function, and this is what we accomplished in the new study," Akinwande said.

The new device falls under the category of memristors, an area of memory research, centred around electrical components with the ability to modify resistance between its two terminals without a need for a third terminal in the middle.

According to the researchers, these can be smaller than currently used memory devices and boast more storage capacity.

They said the new memristor promises a capacity of about 25 terabits per square centimetre, which is about 100 times higher memory density per layer compared with commercially available flash memory devices.
https://archive.is/rVa0M



Scientific Breakthrough! New Device Makes Memristors Act as Neurons
02/10/2020

A memristor is a device that regulates the flow of electrical current in a circuit and remembers the amount of charge that flowed through it. They are non-volatile devices, which means they can retain memory without power. Recently, experts have made a breakthrough in memristors that can make it act like a neuron.

Engineers have been trying to copy the power efficiency and quirky computational skills of the brain for many years, but they cannot do it. They do not have a device that can act like a neuron, one whose behavior is more complicated than any device has ever made.

A new device invented by Hewlett Packard Laboratories' Suhas Kumar, Texas A&M's R. Stanley Williams, and Ziwen Wang, a Stanford student, has met all those requirements. The device outputs simple spikes, burst os spike, self-sustained oscillations, and other processes usually found in the brain using a simple DC voltage as an input.

Most devices can only perform simple spikes, so this new invention is extraordinary. The researchers published their study in the journal Nature (https://archive.is/466y9).

Memristor Breakthrough
The novel device combines resistance capacitance and Mott memristor, with the nanometers-thin niobium oxide (NbO2) layer as the most vital part. A memristor is a device that can hold memories of the charge that previously flowed through them, in the form of resistance.

Engineers have only explored in nanoscale devices the properties of the materials in a Mott transition that could go between insulating and conducting based on their temperature.

Inside the memristor, the transition happens in a nanoscale silver of NbO2 in which when DC voltage is applied, it heats up slightly. It causes it to transition from insulating to conducting. The charge then builts up in the capacitance pours through once that transition happens.

Slowly the device cools, which triggers a transition back to insulating. The result resembles a neuron's action potential in which a spike current flows in the device.

Williams said that they have been working for five years to get that result and noted that many things are going on in that one nanoscale material.

Leon Chua, the inventor of memristor, predicted that there would be regions of chaotic behavior discovered between areas where behavior is unstable if the possible device parameters are mapped. Devices can exist that can act as a neuron at the edge of some of these chaotic regions.

Read Also: Curly the Robot Competes With Professional Curling Athletes (https://archive.is/Fa25r)

Applying it to today's machines
According to Williams, it was Kumar who fine-tuned the material and physical parameters of the device to find a combination that works. This invention is the type that cannot be found accidentally because everything has to be perfect before seeing this characteristic. But once it is made, it becomes very robust and reproducible.

The researchers tested the device by building spiking versions of Boolean logic gates, and then they made a small analog optimization circuit.

According to the researchers, there is still a lot more to do to turn these into practical devices and make them bigger to challenge today's machines. Williams and Kumar plan to explore other possible materials that experience Mott transitions at different temperatures, considering that shifts in NbO2 happen only at 800 degrees Celsius, which only occurs in nanometers thin layer. Scaling it up to millions of devices could pose a big problem.

Meanwhile, other scientists are also researching using vanadium oxide, which can transition at 60 degrees Celsius, better than NbO2. However, that temperature might be too low given that systems in the data center operate ta 100 degrees Celsius, Williams said. There could also be other materials that can be used to achieve the same result, which could be very interesting.
https://archive.is/RGZdL



Space travel impairs mitochondrial function
30/11/2020

Spaceflight is hard on the human body, and our mitochondria are not immune to its pressures.

Space travel presents unique challenges to biology, primarily extended exposure to microgravity and high levels of cosmic radiation. Mitochondria are the organelles responsible for the cell's energy demands, converting sugar into energy, facilitating life. How they react to these challenges is poorly understood. New research from a multidisciplinary team including researchers from the National Aeronautics and Space Administration (NASA), California, and the Georgetown Lombardi Comprehensive Cancer Centre, Washington DC, led by Dr Afshin Beheshti, unites the impact of two threats on this organelle.

'What we found over and over was that something is happening with the mitochondria regulation that throws everything out of whack' Dr Beheshti explained (https://archive.is/MS7zb).

Dr Beheshti's team analysed a breadth of 'multi-omics' data, made possible by NASA's GeneLab, an online 'omics' database consisting of transcriptome, proteome and epigenome data from a variety of experiments involving spaceflight. The group employed this database to take a systems biology approach, looking at multiple species, including humans and mice, isolated human cells, and a variety of tissues, such as muscle and liver.

Their curated dataset was then queried for trends which correlated and overlapped between these diverse samples. The common thread which emerged from the data on gene expression, protein content and epigenetic status of the genome was the signature of changes to mitochondrial activity, across nearly all the samples.

Dr Beheshti 'was completely surprised to see that mitochondria are so important, because they weren't on our radar'. Despite this, the impact of spaceflight on mitochondria was not completely unknown, having previously been observed in soybean seedlings (https://archive.is/ewtAD).

Analysis of blood and urine samples from 59 astronauts and from the NASA Twin Study (https://archive.is/Ne11S) provided physiological evidence of altered mitochondrial function to support the omics data.

Their work, published in the journal Cell (https://archive.is/AZ3uO), shows a universally negative impact of spaceflight on mitochondria and the team believe that impacts on mitochondria, given their critical role in energy generation, could underpin other effects of spaceflight on biology, such as disruption to circadian rhythms and cardiovascular health. Previously identified problems with liver function in astronauts, for example, can now be linked to impaired mitochondria. The team propose a combination of exercise, drugs and diet as a means of minimising the impact of spaceflight on mitochondria in future.

The precise mechanism underlying this impact on mitochondria remains to be uncovered. Nonetheless, the groundwork laid by this study will facilitate future space exploration, which inevitably dictates prolonged periods of spaceflight for humans.
https://archive.is/UW6vC



Comprehensive Multi-omics Analysis Reveals Mitochondrial Stress as a Central Biological Hub for Spaceflight Impact
25/11/2020

Highlights
  • Multi-omics analysis and techniques with NASA’s GeneLab platform
  • The largest cohort of astronaut data to date utilized for analysis
  • Mitochondrial dysregulation driving spaceflight health risks
  • NASA Twin Study data validates mitochondrial dysfunction during space missions

Summary
Spaceflight is known to impose changes on human physiology with unknown molecular etiologies. To reveal these causes, we used a multi-omics, systems biology analytical approach using biomedical profiles from fifty-nine astronauts and data from NASA’s GeneLab derived from hundreds of samples flown in space to determine transcriptomic, proteomic, metabolomic, and epigenetic responses to spaceflight. Overall pathway analyses on the multi-omics datasets showed significant enrichment for mitochondrial processes, as well as innate immunity, chronic inflammation, cell cycle, circadian rhythm, and olfactory functions. Importantly, NASA’s Twin Study provided a platform to confirm several of our principal findings. Evidence of altered mitochondrial function and DNA damage was also found in the urine and blood metabolic data compiled from the astronaut cohort and NASA Twin Study data, indicating mitochondrial stress as a consistent phenotype of spaceflight.

Graphical Abstract
se1kNZ5.png


...
https://archive.is/hTEKS



Study finds hyperbaric oxygen treatments reverse aging process
25/11/2020

6jEVUVa.gif

Human chromosomes (grey) capped by telomeres (white). Credit: PD-NASA; PD-USGOV-NASA

A new study from Tel Aviv University (TAU) and the Shamir Medical Center in Israel indicates that hyperbaric oxygen treatments (HBOT) in healthy aging adults can stop the aging of blood cells and reverse the aging process. In the biological sense, the adults' blood cells actually grow younger as the treatments progress.

The researchers found that a unique protocol of treatments with high-pressure oxygen in a pressure chamber can reverse two major processes associated with aging and its illnesses: the shortening of telomeres (protective regions located at both ends of every chromosome) and the accumulation of old and malfunctioning cells in the body. Focusing on immune cells containing DNA obtained from the participants' blood, the study discovered a lengthening of up to 38% of the telomeres, as well as a decrease of up to 37% in the presence of senescent cells.

The study was led by Professor Shai Efrati of the Sackler School of Medicine and the Sagol School of Neuroscience at TAU and Founder and Director of the Sagol Center of Hyperbaric Medicine at the Shamir Medical Center; and Dr. Amir Hadanny, chief medical research officer of the Sagol Center for Hyperbaric Medicine and Research at the Shamir Medical Center. The clinical trial was conducted as part of a comprehensive Israeli research program that targets aging as a reversible condition.

The paper was published in Aging on November 18, 2020.

"For many years, our team has been engaged in hyperbaric research and therapy—treatments based on protocols of exposure to high-pressure oxygen at various concentrations inside a pressure chamber," Professor Efrati explains. "Our achievements over the years included the improvement of brain functions damaged by age, stroke or brain injury.

"In the current study, we wished to examine the impact of HBOT on healthy and independent aging adults, and to discover whether such treatments can slow down, stop or even reverse the normal aging process at the cellular level."

The researchers exposed 35 healthy individuals aged 64 or over to a series of 60 hyperbaric sessions over a period of 90 days. Each participant provided blood samples before, during and at the end of the treatments, as well as some time after the series of treatments concluded. The researchers then analyzed various immune cells in the blood and compared the results.

The findings indicated that the treatments actually reversed the aging process in two of its major aspects: The telomeres at the ends of the chromosomes grew longer instead of shorter at a rate of 20% to 38% depending on the cell type; and the percentage of senescent cells in the overall cell population was reduced significantly—by 11%-37% depending on cell type.

"Today, telomere shortening is considered the 'holy grail' of the biology of aging," Professor Efrati says. "Researchers around the world are trying to develop pharmacological and environmental interventions that enable telomere elongation. Our HBOT protocol was able to achieve this, proving that the aging process can in fact be reversed at the basic cellular-molecular level."

"Until now, interventions such as lifestyle modifications and intense exercise were shown to have some inhibiting effect on telomere shortening," Dr. Hadanny adds. "But in our study, only three months of HBOT were able to elongate telomeres at rates far beyond any currently available interventions or lifestyle modifications. With this pioneering study, we have opened a door for further research on the cellular impact of HBOT and its potential for reversing the aging process."

Explore further
New hyperbaric oxygen therapy protocol can improve cognitive function of older adults (https://archive.is/Zgel1)

bui6iCa.png

https://archive.is/AmPS0



Hyperbaric oxygen treatments halt aging of blood cells and reverse aging process
22/11/2020

First clinical trial reverses two biological processes associated with aging in human cells.

YrknmYN.png

Image credit: AFTAU

...

The research paper is available at the journal’s web site here (https://archive.is/WwWV8).
https://archive.is/4B1c7

I was wondering if it would mention telomeres... and just when you thought Michael Jackson was right, the jew goes and says something. Let's not forget what's at the forefront of the jew's mind - "How can we make many shekels from this? We make a lot of shekels from funerals and cremations; this would give us a lot more shekels!"



Scientists Identify Gene Responsible for Human Ageing
04/12/2020

New research (https://archive.is/nO8hA) from the University of Wisconsin-Madison, published in Stem Cells, has identified a gene which regulates the ageing of human mesenchymal stem/stromal cells (MSCs).

Reversing Ageing
Cellular reprogramming can reverse ageing in Mesenchymal stem/stromal cells (MSCs). However, the molecular mechanisms by which this is achieved are not well understood. This recent study supported previous findings, demonstrating that rejuvenation was possible by cellular reprogramming. Furthermore, their findings enhanced the understanding of MSC ageing and associated disease. These results provide insight into potential pharmacological strategies to reduce or reverse the ageing process (https://archive.is/wUmjt).

Key Findings
The researchers extracted MSCs from human synovial fluid and reprogrammed them into induced pluripotent stem cells (iPSCs). They then transformed these iPSCs back into MSCs, in effect rejuvenating the MSCs. When comparing the rejuvenated MSCs to the original, non-rejuvenated cells, they found the cellular hallmarks of ageing were greatly reduced in reprogrammed cells. This reduction in ageing-related activities suggests a reversal of cell ageing has occurred.

Next, the scientists genetically analysed cells to investigate any changes in global gene expression as a result of the rejuvenation. They found that the expression of the GATA6 protein was repressed in reprogrammed cells.

The repression of GATA6 also led to an increase in the activity of the sonic hedgehog (SHH) protein and the FOXP1 protein, both essential for early development. Thus, the GATA6/SHH/FOXP1 pathway appears to be a key mechanism which regulates MSC ageing and rejuvenation.

Finally, the team confirmed that OCT4 and KLF4 (two of the four reprogramming genes used to derive iPSCs) were able to regulate GATA6 activity. This is consistent with several previous studies.

Future Direction
Overall, the study demonstrated that MSCs undergo substantial molecular and genetic changes as a result of cellular reprogramming. These changes indicate the amelioration of cell ageing. Most significantly, the outlining of the GATA6/SHH/FOXP1 pathway as a mechanism for cellular age-related activities could have broad implications in regenerative medicine.
https://archive.is/6mQG3



Researchers identify gene responsible for cellular aging
30/11/2020
I9fhZtA.jpg

When mesenchymal stem/stromal cells (MSCs) age, the transcription factor GATA6 is increasingly produced in the cell to induce aging response. By transcription factor-based cellular reprogramming, aged MSCs are rejuvenated with a reduction in GATA6 effects on cellular aging. Credit - AlphaMed Press

Cellular reprogramming can reverse the aging that leads to a decline in the activities and functions of mesenchymal stem/stromal cells (MSCs). This is something that scientists have known for a while. But what they had not figured out is which molecular mechanisms are responsible for this reversal. A study released today in STEM CELLS appears to have solved this mystery. It not only enhances the knowledge of MSC aging and associated diseases, but also provides insight into developing pharmacological strategies to reduce or reverse the aging process.

The research team, made up of scientists at the University of Wisconsin-Madison, relied on cellular reprogramming—a commonly used approach to reverse cell aging—to establish a genetically identical young and old cell model for this study. "While agreeing with previous findings in MSC rejuvenation by cellular reprogramming, our study goes further to provide insight into how reprogrammed MSCs are regulated molecularly to ameliorate the cellular hallmarks of aging," explained lead investigator, Wan-Ju Li, Ph.D., a faculty member in the Department of Orthopedics and Rehabilitation and the Department of Biomedical Engineering.

The researchers began by deriving MSCs from human synovial fluid (SF-MSCs)—that is, the fluid found in the knee, elbow and other joints—and reprogramming them into induced pluripotent stem cells (iPSCs). Then they reverted these iPSCs back to MSCs, in effect rejuvenating the MSCs. "When we compared the reprogrammed MSCs to the non-rejuvenated parental MSCs, we found that aging-related activities were greatly reduced in reprogrammed MSCs compared to those in their parental lines. This indicates a reversal of cell aging," Dr. Li said.

The team next conducted an analysis of the cells to determine if there were any changes in global gene expression resulting from the reprogramming. They found that the expression of GATA6, a protein that plays an important role in gut, lung and heart development, was repressed in the reprogrammed cells compared to the control cells. This repression led to an increase in the activity of a protein essential to embryonic development called sonic hedgehog (SHH) as well as the expression level of yet another protein, FOXP1, necessary for proper development of the brain, heart and lung. "Thus, we identified the GATA6/SHH/FOXP1 pathway as a key mechanism that regulates MSC aging and rejuvenation," Dr. Li said.

"Identification of the GATA6/SHH/FOXP1 pathway in controlling the aging of MSCs is a very important accomplishment," said Dr. Jan Nolta, Editor-in-Chief of STEM CELLS. "Premature aging can thwart the ability to expand these promising cells while maintaining function for clinical use, and enhanced knowledge about the pathways that control differentiation and senescence is highly valuable."

To determine which of the Yamanaka transcription factors (four reprogramming genes used to derive iPSCs) were involved in repressing GATA6 in the iPSCs, the team analyzed GATA6 expression in response to the knockdown of each factor. This yielded the information that only OCT4 and KLF4 are able to regulate GATA6 activity, a finding consistent with that of several previous studies.

"Overall, we were able to demonstrate that SF-MSCs undergo substantial changes in properties and functions as a result of cellular reprogramming. These changes in iPSC-MSCs collectively indicate amelioration of cell aging. Most significantly, we were able to identify the GATA6/SHH/FOXP1 signaling pathway as an underlying mechanism that controls cell aging-related activities," Dr. Li said.

"We believe our findings will help improve the understanding of MSC aging and its significance in regenerative medicine," he concluded.

Explore further
Human iPSC-derived MSCs from aged individuals acquire a rejuvenation signature (https://archive.is/Mn2c9)
https://archive.is/oxiKP



Scientists create diamonds at room temperature in minutes
20/11/2020
EeOhePE.jpg

PHD scholar Xingshuo Huang from the Australian National University holds the diamond anvil that the team used to make the lab diamonds.

Diamonds might be forever, but that doesn't mean they have to take eons to form.
The gemstones are usually created after carbon is crushed and heated far beneath the Earth's surface over billions of years -- which is what makes them so coveted.
Now, scientists in Australia say they have sped up the process into just a matter of minutes -- and at room temperature.

An international team of researchers led by the Australian National University (ANU) and RMIT University in Melbourne, Australia said Wednesday they have created two types of diamond at room temperature by using high pressure equivalent to 640 African elephants balancing on the tip of a ballet shoe.

The researchers said they were able to create two types of structurally distinct diamonds -- one similar to those typically worn in jewelery, and another type called Lonsdaleite, which is found naturally at the site of meteorite impacts and is harder than most diamonds.
Synthetic diamonds are not themselves new, and have already been created in labs since the 1940s in a bid to find cheaper, ethical and environmentally friendly stones.

But researchers were excited to create such diamonds at room temperature, especially the harder Lonsdaleite diamond, which has the potential to be used to cut through "ultra-solid" materials on mining sites, they said.

"Creating more of this rare but super useful diamond is the long-term aim of this work," said Xingshuo Huang, an ANU scholar working on the project. "Being able to make two types of diamonds at room temperature was exciting to achieve for the first time in our lab."
Lab grown diamonds are usually created by carbon being subjected to intense heat (https://archive.is/b9Qp8).

A huge twisting, sliding force
To form the diamonds, researchers applied immense pressure to create a "twisting or sliding force" that they believe caused the carbon atoms to move into place, said Jodie Bradby, a physics professor at ANU.

"Natural diamonds are usually formed over billions of years, about 150 kilometers (about 93 miles) deep in the Earth where there are high pressures and temperatures above 1,000 degrees Celsius (1,832 degrees Fahrenheit)," she said. "The twist in the story is how we apply the pressure."

Y5PIciz.jpg

This close up image shows the diamond "rivers".

Dougal McCulloch, physics professor at RMIT who co-lead the research, and his team then used advanced electron microscopy techniques to take slices from the experimental samples to better understand how they were formed.

When the team studied the samples they found veins of both regular and the Lonsdaleite diamonds running through.

"Seeing these little 'rivers' of Lonsdaleite and regular diamond for the first time was just amazing and really helps us understand how they might form," McCulloch said.
Researchers from The University of Sydney and Oak Ridge National Laboratory, in Tennessee, US were also involved in the research.

Related Article
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This entrepreneur says he's making diamonds 'from the sky'
https://archive.is/w04D0



Scientists defy nature to make insta-bling at room temperature
An international team has made diamonds in minutes in a laboratory at room temperature – a process that normally takes billions of years, huge amounts of pressure and super-hot temperatures.

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PhD candidate Brenton Cook and Professor Dougal McCulloch in the RMIT Microscopy and Microanalysis Facility

...
https://archive.is/ovxhJ

It has been known that commercially-purchasable diamonds can be created in laboratories/factories, as well. I saw something which showed the size of a diamond in a pressing machine thing, and the machine around the tiny-in-comparison diamond, was big, sort of like having a giant's hand crushing a usual-sized almont "nut" (cough) or something. Oh, and did I say that they still cost a lot of shekels to buy, despite them being mass-produced now?!

According to the Mohs scale, diamond is the strongest substance. It can be cut only by another diamond (the last I knew).

Along the lines of the "twisting or sliding force" which they believe moves atoms into place - I wondered if we could get some mercury, freeze it to low-enough temperatures, and remove one of its protons thereby turning it from mercury into gold, a sort of futuristic Midas touch or philosopher's stone (because these things are "legend" and "primitive", of course). It is, apparently, "possible to transmute mercury into gold by making it unstable so it decays [https://archive.is/wx6iV]. Decay, freeze, whatever.




Earth’s Water Came from Enstatite Chondrite-Like Asteroids, Study Suggests
LOFXRME.jpg

A piece of the enstatite chondrite meteorite Sahara 97096. Image credit - Christine Fieni/Laurette Piani/French National Museum of Natural History.

A type of meteorite called an enstatite chondrite has similar isotopic composition to terrestrial rocks and thus may be representative of the material that formed Earth. A new study (https://archive.is/Mb1tk) published in the journal Science shows that these meteorites contain sufficient hydrogen to have delivered to Earth at least three times the mass of water in its oceans.

Enstatite chondrites are space rocks forged from the nebula that formed the Solar System.

They are rare, making up only about 2% of known meteorites in collections. But their isotopic similarity to terrestrial rocks make them particularly compelling.

They have similar oxygen, titanium and calcium isotopes as Earth, and the new study showed that their hydrogen and nitrogen isotopes are similar to Earth’s, too.

“Our discovery shows that the Earth’s building blocks might have significantly contributed to the Earth’s water,” said Dr. Laurette Piani, a researcher at the Université de Lorraine.

“Hydrogen-bearing material was present in the inner Solar System at the time of the rocky planet formation, even though the temperatures were too high for water to condense.”

The building blocks of Earth are often presumed to be dry. They come from inner zones of the Solar System where temperatures would have been too high for water to condense and come together with other solids during planet formation.

The meteorites provide a clue that water didn’t have to come from far away.

“The most interesting part of the discovery for me is that enstatite chondrites, which were believed to be almost dry, contain an unexpectedly high abundance of water,” said Dr. Lionel Vacher, a postdoctoral researcher at Washington University in St. Louis.

“If enstatite chondrites were effectively the building blocks of our planet — as strongly suggested by their similar isotopic compositions — this result implies that these types of chondrites supplied enough water to Earth to explain the origin of Earth’s water, which is amazing!”

The team also proposes that a large amount of the atmospheric nitrogen — the most abundant component of the Earth’s atmosphere — could have come from the enstatite chondrites.

“Only a few pristine enstatite chondrites exist: ones that were not altered on their asteroid nor on Earth,” Dr. Piani said.

“In our study, we have carefully selected the enstatite chondrite meteorites and applied a special analytical procedure to avoid being biased by the input of terrestrial water.”

Coupling conventional mass spectrometry and secondary ion mass spectrometry allowed the scientists to precisely measure the content and composition of the small amounts of water in the meteorites.

“Prior to this study, it was commonly assumed that enstatite chondrites formed close to the Sun,” Dr. Piani said.

“These chondrites were thus commonly considered dry, and this frequently reasserted assumption has probably prevented any exhaustive analyses to be done for hydrogen.”

Laurette Piani et al. 2020. Earth’s water may have been inherited from material similar to enstatite chondrite meteorites. Science 369 (6507): 1110-1113; doi: 10.1126/science.aba1948
https://archive.is/3CxAL



Meteorite study suggests Earth may have been wet since it formed
Enstatite chondrite meteorites, once considered 'dry,' contain enough water to fill the oceans -- and then some
https://archive.is/6rNyu



The Earth may have been wet from the very start
A new study finds the rocks that first formed Earth carried with them enough hydrogen for three times the water we have today.
https://archive.is/KGn7y



Mistakes and errors in the articles above are by the respective authours of the articles.

This is just like reading a popular science magazine, thank you so much Fancy.
 
HP. Hoodedcobra666 said:
Satan_is_our_Father666 said:
HP. Hoodedcobra666 said:
We are entering a wonderful age of discovery and for science, and this is a reason to oppose the enemy now to avoid the worst later.

Just imagine the possibilities of all of this. The enemy has to fail at all costs to drag down the United States. A lot of great things will arise in the next decades.

The only thoughts of the slimy jew among all of these wonderful things, is to just make people drones or something. They never care for the bigger picture.
...

HAIL SATAN FOREVER!

Your worry is more based on what could wrong rather than what could go right. I tend to think of things in a more positive light. And science will assist on many things, but can breed monstrosities. The same thing goes for spiritual power. Some people may use it for nefarious purposes, but it can't be that it's restrained as there is no good either.

Problems arise when all of the scientific advancement is not followed up with spiritual awareness. But this line will meet the other in the future after time passes. As we are going right now, there is hope for this at least.

The combination of technological and scientific discovery is a manifestation of one aspect and level of the mind. If it follows up with the rest of the spiritual advancement, there shouldn't be fear.

IMO, the enemy being in power and trying to bind these things, is the only worrisome thing.

You can be in the Stone Age and people will still do braindead things that can cause mass destruction. What changes with technology is the magnitude of this. The only way to avoid this is to change humans and in the case of the enemy, remove them from power.

I agree. You have wise and advanced people in power and teaching others there will be a much better outcome. If you have the enemy the outcome might not be so good at all. What we have to do is just keep up the spiritual warfare. I have to think somewhat that with better energies around in the world people will be maybe a little less inclined to be destructive no matter what even the ones that are not open. Cities and areas that have positive energy for example are known to have less crime and problems. This was known by psychic people for a long time and why they often sought to live in an area that was more positive in energy. Even people who know nothing about Satanism but sense things know this. So if the world in general has a lot more positive energy and higher vibration (the world is starting to rise in vibration somewhat) there will be less problems due to that alone. Cause the enemy curses caused most the problems. What we are doing is not just removing curses from us but everyone.

So I dont have any negative feelings about more technology and discoveries right now. Maybe some of them can help clean up the mess with the environment. That would be cool. I think we are fine and we will be fine. Maybe things are even going better than the Gods thought they would from some of the things posted by Maxine and others.

We can achieve the things that new ageism and enemy religions falsely taught they would bring. Like world peace, brotherhood, a better society, a more kind world, eventually a paradise world and finally the big one eternal life in paradise (ours will be 1000 times better than their pie in the sky heaven cause we won't be slaves)

The enemy lied and said they could bring it but bought the opposite. We are the ones who can bring it.
 
In relation to science, I wonder what people here think of Theoria Apophasis' channel besides being a photographer, he has a lot of deep science that connects even further from what I learned from here.
 
I thought I might have shared these before, but I can't seem to find them. Either way, at least this information is being shared.

  • Scientists claim big advance in using DNA to store data
  • It's in the genes – data storage turns to DNA



BBC
Scientists claim big advance in using DNA to store data
1/12/2021

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Image source - Science Photo Library
If stored as DNA, every film ever made could be stored in a space smaller than a sugar cube

Scientists say they have made a major step forward in efforts to store information as molecules of DNA, which are more compact and long-lasting than other options. The magnetic hard drives we currently currently to store computer data can take up lots of space and they have to be replaced over time. Using life's preferred storage medium to back up our precious data would allow vast amounts of information to be archived in tiny molecules.

The data would also last thousands of years, according to scientists. A team in Atlanta, US, has now developed a chip that they say could improve on existing forms of DNA storage by a factor of 100. "The density of features on our new chip is [approximately] 100x higher than current commercial devices", Nicholas Guise, senior research scientist at Georgia Tech Research Institute (GTRI), told BBC News. "So once we add all the control electronics - which is what we're doing over the next year of the programme - we expect something like a 100x improvement over existing technology for DNA data storage."

The technology works by growing unique strands of DNA one building block at a time. These building blocks are known as bases - four distinct chemical units that make up the DNA molecule. They are - adenine, cytosine, guanine and thymine.

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Image source - Sean McNeil
The microchip will be used for growing multiple strands of DNA in parallel

The bases can then be used to encode information, in a way that's analogous to the strings of ones and zeroes (binary code) that carry data in traditional computing. There are different potential ways to store this information in DNA - for example, a zero in binary code could be represented by the bases adenine or cytosine and a one might be represented by guanine or thymine. Alternatively, a one and zero could be mapped to just two of the four bases.

Scientists have said that, if formatted in DNA, every film ever made could fit inside a volume smaller than a sugar cube. Given how compact and reliable it is, it's not surprising there is now broad interest in DNA as the next medium for archiving data that needs to be kept indefinitely. The structures on the chip used to grow the DNA are called microwells and are a few hundred nanometres deep - less than the thickness of a sheet of paper. The current prototype microchip is about 2.5cm (one-inch) square and includes multiple microwells, allowing several DNA strands to be synthesised in parallel. This will allow larger amounts of DNA to be grown in a shorter space of time.

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How DNA can be used to store computer data

MICROCHIP?! - Scientists claim big advance in using DNA to store data
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https://www.bitchute.com/video/03KtyvgmT1ie

Because it's a prototype, not all the microwells are wired up yet. This means the total amount of DNA data that can be written with this particular chip is currently less-than what leading synthesis companies can produce on commercial chips; however, Dr Guise explained that when everything's up and running that will change. The current record for DNA digital data storage is around 200MB, with single synthesis runs lasting about 24 hours, but the new technology could write 100 times more DNA data in the same amount of time.

The high cost of DNA storage has so far restricted the technology to "boutique customers", such as those seeking to archive information in time capsules. The team at GTRI believes their work could help reshape the cost curve. It has partnered with two California biotech companies to make a commercially-viable demonstration of the technology - Twist Bioscience and Roswell Biotechnologies.

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Image source - Sean McNeil
GTRI's Nicholas Guise tests electronics on the microchip

DNA data storage won't initially replace server farms for information that must be accessed quickly and often. Because of the time required for reading the sequence, the technique would be most useful for information that must be kept available for a long time, but accessed infrequently. This type of data is currently stored on magnetic tapes which should be replaced around every 10 years. With DNA, however, "as long as you keep the temperature low enough, the data will survive for thousands of years, so the cost of ownership drops to almost zero", Dr Guise explained.

"It only costs much money to write the DNA once at the beginning and then to read the DNA at the end. If we can get the cost of this technology competitive with the cost of writing data magnetically, the cost of storing and maintaining information in DNA over many years should be lower."

DNA storage has a higher error rate than conventional hard drive storage. In collaboration with the University of Washington, GTRI researchers have come up with a way of identifying and correcting those errors.The work has been backed by the Intelligence Advanced Research Projects Activity (IARPA), which supports science geared towards overcoming challenges relevant to the US intelligence community.

Related
Scientists write film into bacterial DNA
https://archive.ph/DsP8F
https://archive.ph/gXuLo
"life's preferred storage medium"?
"so the cost of ownership drops to almost zero" - so after you've been buried (not cremated), then you are owned by the state or by a commercial business. The cost would be nearly 0, because maintenance would be required. Hmmm... The Matrix? The lie in that film series is that the victims are... well, barely alive.



ec.europa.eu
It's in the genes – data storage turns to DNA
22 April 2013
"It's in your genes!" How often have you been reminded by friends or relatives that you look the way you do because of the genetic code stored in your DNA? The next time you hear this expression used, you might stop to wonder what else could be stored in those genes.

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Nick Goldman is a scientist at the European Bioinformatics Institute at Cambridge in the UK ©EMBL

According to the latest research to come out of the Cambridge-based European Bioinformatics Institute (EBI), DNA is capable of more than just storing genetic information alone - it also has the potential to store massive volumes of man-made data. The research is now getting EU funding that could go towards refining the technique so that it could be scaled up to store all of the data that exists on Earth – estimated to be three zettabytes, or 3 000 billion billion bytes – which, for those who don't think in 'bytes', is roughly equivalent to a pile of 750 billion DVDs. In the future, a cup of DNA could store 100 million hours of video.

Storing information in a miniscule form that cuts down on space and does away with the need for energy guzzling and costly hard disks would be a timely innovation in the digital age. As more and more data is generated, the need for economical and durable forms of data storage also rises. It was this pressing issue that prompted the key authours of the EBI research project, Nick Goldman and EBI Associate Director Ewan Birney, to act.

"At the Institute, we share biological data with other scientists to improve their insights into life", said Goldman. "We add value to it and send it back into the research community via the Internet, but we realised that, as the volume of biological data we receive grows exponentially, our budget to handle and store it does not. Disks are expensive. We needed to find a way of storing large volumes of data in a small space, cheaply – and ensure that it could be retrieved efficiently."

The pair hit upon their approach to resolving the problem three years ago. "Ewan and I were chatting one evening after a work conference in Hamburg. We were joking about, thrashing out ideas for alternative data storage methods, and then, after we’d batted a few ideas back and forth, we just turned to each other and said, 'How about using DNA?'."

Much of the funding for such research at the non-profit EBI comes from the European Union, under the Directorate-General Research & Innovation's Sixth and Seventh Framework Programmes. In 2012, the Institute received EUR 7.3 million from the European Commission.

Before they started, Goldman and Birney put together a project research team at the EBI, which forms part of the EU-wide European Molecular Biology Laboratory (EMBL). They also enlisted another actor – Agilent Technologies, a California-based biomedical technologies company with expertise in writing DNA – to complete the research network. "Agilent saw it as a challenge and a fun piece of research", says Goldman. "They provided the required DNA samples to us for free."

Shall I compare thee to a DNA?
"We already know that DNA is a robust way to store information because we can extract it from bones of woolly mammoths, which date back tens of thousands of years, and still make sense of it. It is also incredibly small, dense and does not need any power for storage, so shipping and keeping it is easy", Goldman said.

The experiment to see if they could actually use DNA to store information took place in three stages:

1. First up were the EBI team. "Our role was to invent a DNA code into which digital information could be translated", said Goldman. Typically, a file on a computer hard disk is stored in binary code, comprising zeros and ones. The computer ‘knows’ the rules of the code and translates the information it receives accordingly. It was up to the EBI team to rewrite the binary code into a DNA sequence on a computer file.

The coding system of DNA – or deoxyribonucleic acid – is built on four nitrogen bases, identified by the letters A (adenine), C (cytosine), G (guanine) and T (thymine). The trick was to write a DNA sequence where the same letters were never repeated. One way of decreasing the risk of errors was to write only short strings of DNA.

"We figured - let’s break up the code into lots of overlapping fragments going in both directions, with indexing information showing where each fragment belongs in the overall code, and make a coding scheme that doesn’t allow repeats. That way, you would have to have the same error on four different fragments for it to fail – and that would be very rare", Birney said.

2. Once they had their DNA sequence design in place, they used it to encode an MP3 clip of Martin Luther King's famous "I have a dream" speech, a photo of the EMBL-EBI lab, an image of the famous DNA double helix structure as identified by James Watson and Francis Crick in 1953, and a text file of all 154 of Shakespeare's sonnets. The encoded computer files were flown to Dr Emily Leproust of Agilent Technologies in California. "We downloaded the files from the web and used them to synthesise hundreds of thousands of pieces of DNA. The result looks like a tiny speck of dust", Leproust said.

During the synthesis process, Agilent manufactured DNA that matched the DNA sequence sent to them by the EBI. Using technology that is a bit like an inkjet printer, they fired the encoded DNA in the form of miniscule droplets onto a microscope's glass slide. The fluid was then freeze-dried and the resulting speck of dust containing 739 kilobytes of data was flown back to Cambridge.

3. Reconstituted in water, the substance was shipped on to the EMBL’s Heidelberg office in Germany, where it was read back by sequencing machinery and the digital information reconstructed with 100 percent accuracy, the researchers said. The EBI exists in large part thanks to funds received from the EMBL's 20 member states, but Goldman sees EU funding as playing a vital indirect role in expanding its work. "In this research project, for example, we really benefited from being able to call on team members whose skills had been honed on schemes funded by the EU and who could assist in data analysis and data modelling. Sometimes, of course, the EBI gains essential hardware through funding, but here it was the EU's 'investment in people' that counted for us."

More of a long-term thing
So, do the results of their research mean the end of the hard disk? Not quite yet. At the moment, the team sees its main application as storing information that needs to be archived for a long period of time and accessed on an infrequent basis.

"From a cost point of view, DNA data storage really comes in to its own over the long-term", says Goldman. "The one-off cost for DNA sequencing is still very high, but once that expenditure has been made, it becomes a very cheap way of archiving information. With DNA, maintenance costs are minimal as the cost of endlessly re-transferring information from one outdated medium to another – such as video tape to CD – can be dispensed with. It costs virtually nothing to store and - unlike video tape which degrades rapidly with time - lasts thousands of years."

People will start using DNA to store data within the next 50 years, Goldman believes, as the cost of DNA sequencing goes down. "Right now, I could see it as providing an excellent way of storing data that is now held on magnetic tapes – it's not impossible to imagine that those vast dusty archives of tapes, whose corridors are currently patrolled by data retrieval robots, could be done away with once and for all with our method."

More info
European Bioinformatics Institute
European Molecular Biology Laboratory
Agilent Technologies
https://archive.ph/W6947
"'Shall I compare thee to a' DNA"?

"At the Institute, we share biological data with other scientists to improve their insights into life"
Trust a... erm... gold-standard... peughmann to share personal information with companies.

Does anyone think this European Molecular Biology Laboratory (EMBL) are attempting to get an EMBLem - or provide one for others to follow?
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You have to love dirty morals and ethics!

"So, do the results of their research mean the end of the hard disk? Not quite yet."
Of course not. People would not accept it. Things have to be done slowly, over time, to help people not think about things properly while they're distracted by other things, and to ease them into things instead.
 

Al Jilwah: Chapter IV

"It is my desire that all my followers unite in a bond of unity, lest those who are without prevail against them." - Satan

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