It depends. If the Sun is the ruler of the Chart or the co ruler then of course. A Sun in Leo in the 7th house is also much stronger than a Sun in Aquarius in the 6th house for example.
An aspect with Jupier also makes a planet stronger, and aspects with Neptune and Saturn make it weaker.
Are you talking about dispositors? Like the dispositor to one's Sun? The way you framed your questions sounds like it. For anyone wondering, dispositors are planets that rule the sign another planet is in. Like if you have your Sun in Cancer, the Moon is a dispositor to your Sun. I have found this theory about dispositors to be rather inaccurate personally.