Ever met a stoner druggie type? They know how much weed, crack, etc damages their mind and body but do it anyway. Then there are the types that constantly wastes themselves away in some fantasy world, like video games and whatnot for absurd amounts of time for no reason other than "life sux, video games are LEET". Then there are the people that are completely absorbed into the enemy programs that they are unable to see past anything in front of them. Basically these people and many more who are just so "woke" about life being meaningless that they won't do anything with their life and purposefully waste away.
These people that are unable to help themselves because they are just too far gone that nothing you say or do will make them change their self destructive ways. These people will find the truth when its too late for themselves and nothing they do can fix it. That's how i interpret that line.