Physical deformities and disfigurements can arise from a combination of factors, including genetics, environmental factors, and karma. Karma can accumulate over multiple lifetimes for better or worse, which influences one's circumstances in the present lifetime.
For example, individuals who endured extreme suffering, such as forced labor in oppressive regimes (gulag camps) or other unbearable conditions, leaves an infliction on the soul. This infliction carry residual karmic imprints that manifest physically, which brings serious life challenges in their next incarnation. However, this does not necessarily mean they were "evil" or "degenerate" in their past lives. Without spiritual knowledge on how to remove negative karma from their soul, people will remain at the mercy of fate.
As for "evil" people and karma; Certain diseases are more prevalent within the Jewish race due to their karmic heritage of a disaster. The one you are referring to in the link is likely called Proteus Syndrome, aka, the Elephant Syndrome, which is more prevalent among Jewish ancestry. Some diseases are also exclusively Jewish, such as Tay Sachs of Ashkenazi descent. Other notable diseases are, for example, Gaucher Type 1 and Bloom Syndrome.
